Prof Rose Hayeshi
Medicine and you: How your body and genes influence drug actions (read more)
Medicine and you: How your body and genes influence drug actions
Prof Rose Hayeshi
This lecture provides an overview of drug metabolism and drug transporters, pharmacokinetics and pharmacogenomics. It explores how these factors influence the absorption, distribution, metabolism and excretion (ADME) of medications, as well as the role of genetic variations in drug responses. The lecture also delves into the use of nanoparticles to enhance drug solubility and bioavailability and discusses the impact of drug-metabolising enzymes on drug-drug interactions. By understanding these fundamental concepts, individuals can gain a deeper appreciation for the complexities of drug therapy and the potential benefits of personalised medicine, which leverages genetic information to optimise treatment plans.
Prof Minja Gerber
Skin: More than just a dermo cover (read more)
Skin: More than just a dermo cover
Prof Minja Gerber
The skin, composed of three layers (epidermis, dermis, and hypodermis) is the body's largest organ. The outer epidermal layer, the stratum corneum, is lipophilic and serves as the primary barrier, while deeper skin layers are more hydrophilic. However, not all active pharmaceutical ingredients (APIs) are suitable for transdermal and topical drug delivery, since most lack the optimal physicochemical properties for effective skin permeation. To overcome this, penetration enhancers and drug delivery vehicles can be utilised to improve and/or target drug delivery. In this lecture, I trace the evolution of transdermal drug delivery and explore the exciting new possibilities that could transform dreams and innovative ideas into reality in the future.
Prof Ankebé Kruger
Sports Psychology: The human behind the athlete (read more)
Sports Psychology: The human behind the athlete
Prof Ankebé Kruger
Sports Psychology studies athletes' behaviour and applies this knowledge to enhance their performance and well-being. University student-athletes face unique mental health challenges in balancing academic and athletics demands, often experiencing higher rates of anxiety, depression, eating disorders and substance abuse. Early identification and intervention by sports psychologists can prevent severe mental health issues and improve treatment outcomes. Despite many stressors, student-athletes often underutilise psychological services due to stigma and lack of awareness. Research can inform policies and develop interventions to support student-athletes' mental health, enhancing their academic and athletic performance and overall quality of life.
Prof Elmari Deacon
SMILE with Diabetes (read more)
SMILE with Diabetes
Prof Elmari Deacon
The SMILE with Diabetes project aims to investigate psychosocial variables in adjusting to diabetes management behaviour in a positive psychology framework. In my research, I focus on illness perception and meaning-making and how its interaction influences adjusting to diabetes care plans and experiencing positive outcomes. Studies with adolescents and adults living with well-controlled and uncontrolled type 1 and 2 diabetes indicate that both groups experience emotional distress and are being treated differently. Still, the well-controlled groups can redefine the condition as manageable, focusing on actions that assist them to experience positive outcomes. The meaning-making model (Park, 2013) provides insight into the process of integrating living with the condition into daily routines by explaining how global beliefs are challenged by the diagnosis of diabetes, leading to distress, but also providing an opportunity to revisit perceptions and create new meaning and positive outcomes. Several interventions have been developed, including a web-based programme to assist adolescents in adjusting to diabetes technologies, and cognitive behavioural therapy (CBT) guidelines for healthcare practitioners. Future projects include the development of a web-based intervention for adults living with type 2 diabetes, exploring the lived experience of self-compassion in diabetes management, and conducting an explorative case study on the successful management of type 2 diabetes in an identified private practice.